115514-18-6Relevant articles and documents
Conformational Mimicry. 1. 1,5-Disubstituted Tetrazole Ring as a Surrogate for the Cis Amide Bond
Zabrocki, Janusz,Smith, G. David,Dunbar, James B. Jr.,Iijima, Hiroshi,Marshall, Garland R.
, p. 5875 - 5880 (1988)
Assessment of the conformational implications of chemical modification is an important aspect of analogue design.A new procedure, the assessment of conformational mimicry, which determines the percentage of sterically accessible conformations for the pare
Immunomodulators
-
, (2016/08/29)
The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.