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Usage

Uses

Used in Pharmaceutical Synthesis:
BDP is utilized as a building block in the synthesis of a range of pharmaceutical compounds. Its unique structure allows for the creation of new molecules with potential therapeutic properties, contributing to the development of novel drugs.
Used in Research as a Ligand:
In the field of research, BDP serves as a ligand for metal ions. This application is crucial for studying the interactions between metal ions and organic compounds, which can lead to a better understanding of chemical reactions and the development of new materials.
Used in Coordination Polymer Development:
BDP is also employed in the development of coordination polymers, which are materials with potential applications in various industries, including electronics, energy storage, and catalysis. 1-(2-Bromophenyl)-3,5-dimethyl-1H-pyrazole's ability to form stable complexes with metal ions makes it a valuable component in the design of these advanced materials.
Used in Insecticidal and Fungicidal Applications:
BDP has been investigated for its potential insecticidal and fungicidal properties, making it a candidate for use in the agricultural industry to protect crops from pests and diseases. Its effectiveness in controlling insects and fungi could lead to the development of new, environmentally friendly pest control solutions.

Upstream product

• 50709-33-6 2-bromophenylhydrazine hydrochloride 
• 123-54-6 acetylacetone 
• 16732-66-4 2-bromophenylhydrazine 

Relevant academic research and scientific papers

Oxone-DMSO Triggered Methylene Insertion and C(sp2)-C(sp3)-H-C(sp2) Bond Formation to Access Functional Bis-Heterocycles

Metal-free insertion of a methylene group was achieved for the construction of a new C(sp2)-C(sp3)-H-C(sp2) bond in order to prepare novel bis-heterocyclic scaffolds. The complete mechanistic investigations included experimental study and DFT calculations, and various symmetric and unsymmetric bis-pyrazoles as well as other pyrazole-based bis-heterocyclic molecules were prepared in moderate to high yields. Further modification of the bridged methylene group in the unsymmetric pyrazoles generated a chiral center to extend the scope of this method.

Steric vis-à-vis electronic influence of phosphines on biaryl motif: Ligand design for coupling reactions with Chloroarenes

In order to assess relative contribution of steric factors and electron-richness of phosphine ligands on biaryl-type scaffolds, a set of 1-aryl-pyrazole/pyrrole derived ligands L1-L6 featuring either aryldicyclohexylphosphino or aryldiphenylphosphino donor group was synthesized. A bidentate coordination mode of ligands L1 or L2 was evident from a representative crystal structure that implied a possible hemilabile participation to facilitate catalytic steps. With N-arylpyrroles (L3-L5), where the second nitrogen donor on the heterocycle is absent, coupling reactions of unactivated chloroarenes still proceeded with comparable efficiency. Thus, suitably endowed triarylphosphines were found to be as efficient as more expensive aryldialkylphosphine analogs in reactions with chloroarenes, extending the scope of ligand design.

Steric vis-??-vis electronic influence of phosphines on biaryl motif: Ligand design for coupling reactions with Chloroarenes

In order to assess relative contribution of steric factors and electron-richness of phosphine ligands on biaryl-type scaffolds, a set of 1-aryl-pyrazole/pyrrole derived ligands L1-L6 featuring either aryldicyclohexylphosphino or aryldiphenylphosphino donor group was synthesized. A bidentate coordination mode of ligands L1 or L2 was evident from a representative crystal structure that implied a possible hemilabile participation to facilitate catalytic steps. With N-arylpyrroles (L3-L5), where the second nitrogen donor on the heterocycle is absent, coupling reactions of unactivated chloroarenes still proceeded with comparable efficiency. Thus, suitably endowed triarylphosphines were found to be as efficient as more expensive aryldialkylphosphine analogs in reactions with chloroarenes, extending the scope of ligand design.