115572-81-1

Basic information

• Product Name: (-)-1-(benzyloxycarbonyl)-2(S)-tert-butyl-3-<(S)methyl(methoxycarbonyl)methyl>-5(S)-methylimidazolidin-4-one
• CAS NO: 115572-81-1
• Molecular Weight: 376.453
• Mol File: 115572-81-1.mol

Chemical Properties

• CAS DataBase Reference: (-)-1-(benzyloxycarbonyl)-2(S)-tert-butyl-3-<(S)methyl(methoxycarbonyl)methyl>-5(S)-methylimidazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-1-(benzyloxycarbonyl)-2(S)-tert-butyl-3-<(S)methyl(methoxycarbonyl)methyl>-5(S)-methylimidazolidin-4-one(115572-81-1)
• EPA Substance Registry System: (-)-1-(benzyloxycarbonyl)-2(S)-tert-butyl-3-<(S)methyl(methoxycarbonyl)methyl>-5(S)-methylimidazolidin-4-one(115572-81-1)

Safety Data

• Hazardous Substances Data: 115572-81-1(Hazardous Substances Data)

Upstream product

• 115572-70-8 (-)-1-(benzyloxycarbonyl)-2(S)-tert-butyl-3-<(methoxycarbonyl)methyl>-5(S)-methylimidazolidin-4-one 
• 74-88-4 methyl iodide 

Relevant articles and documents

Stereoselective Alkylation of Glycine Units in Dipeptide Derivatives: "Chirality Transfer" via a Pivalaldehyde N,N-Acetal Center

Dipeptide esters (of glycylglycine, glycylalanine, alanylglycine) and aldehydes (isobutyraldehyde, pivalaldehyde, benzaldehyde) are condensed to (4-oxoimidazolidin-3-yl)acetates and -propionates (1-3).Lithium enolates of these derivatives, are generated (

178. Alkylation of Imidazolidinone Dipeptide Derivatives: Preparation of Enantiomerically Pure Di- and Tripeptides by "Chirality Transfer" via a Pivalaldehyde N,N-Acetal Center

Glycylglycine, glycyl-(S)-alanine, and (S)-alanylglycine esters are cyclized through pivalaldehyde imines to give dipeptide-derived 3-(benzyloxycarbonyl)-2-(tert-butyl)-5-oxoimidazolidine-1-acetates 1-3.These are alkylated diastereoselecively by Li-enolat