115583-79-4Relevant academic research and scientific papers
1,3-Dipolar Cycloaddition Reactions of 1-Aryl-N-methyl-2-(1H-azol-1-yl)-ethanimine N-Oxides to Olefins
Mullen, George B.,Bennett, Grace A.,Swift, Patricia A.,Marinyak, David M.,Dormer, Peter G.,Georgiev, Vassil St.
, p. 105 - 107 (2007/10/02)
The regio- and stereoselectivity of the 1,3-dipolar cycloaddition reaction of 1-aryl-N-methyl-2-(1H-azol-1-yl)ethanimine N-oxides 6 to monosubstituted olefins 7 were investigated.The reaction is regioselective, leading to the corresponding C-5 substituted isoxazolidines 8/9 as cis/trans diastereomeric mixtures.The cis isomers, which are the predominant species of the mixtures, are readily separated by flash chromatography on neutral silica gel.
