115610-36-1

Basic information

• Product Name: Benzoic acid,2-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-
• Synonyms: Benzoic acid,2-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]amino]- (9CI); Benzoic acid, 2-[[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]amino]-,(E)-; Avenanthramide 1p; Avenanthramide D; Dianthramide P;N-(E)-p-Coumaroylanthranilic acid
• CAS NO: 115610-36-1
• Molecular Formula: C16H13 N O4
• Molecular Weight: 283.284
• Mol File: 115610-36-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzoic acid,2-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid,2-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-(115610-36-1)
• EPA Substance Registry System: Benzoic acid,2-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-(115610-36-1)

Safety Data

• Hazardous Substances Data: 115610-36-1(Hazardous Substances Data)

Upstream product

• 53947-84-5 2-[(2-carboxyacetyl)amino]benzoic acid 
• 123-08-0 4-hydroxy-benzaldehyde 
• 53901-95-4 p-acetoxycinnamoyl chloride 
• 27542-85-4 4-acetoxycinnamic acid 
• 118-92-3 anthranilic acid 
• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 130514-72-6 2-[(E)-2-(4-Hydroxy-phenyl)-vinyl]-benzo[d][1,3]oxazin-4-one 

Relevant articles and documents

Preparation method of avenanthramide and derivative thereof

The invention provides a preparation method of avenanthramide and a derivative thereof. The avenanthramide and the derivative thereof are synthesized and obtained by mainly utilizing an organic acid and aminobenzoic acid as major reactants. The method is

COMBINATION THERAPY OF ARTHRITIS WITH TRANILAST

Combination therapy is disclosed herein for the treatment an arthritic condition (e.g. rheumatoid arthritis, osteoarthritis or psoriatic arthritis). The therapies disclosed herein comprise administering tranilast or an analogous compound in combination wi

Avenanthramides in oats (Avena sativa L.) and structure-antioxidant activity relationships

Eight avenanthramides, amides of anthranilic acid (1) and 5-hydroxyanthranilic acid (2), respectively, and the four cinnamic acids p-coumaric (p), caffeic (c), ferulic (f), and sinapic (s) acid, were synthesized for identification in oat extracts and for structure-antioxidant activity studies. Three compounds (2p, 2c, and 2f) were found in oat extracts. As assessed by the reactivity toward 1,1-diphenyl-2-picrylhydrazyl (DPPH), all avenanthramides except 1p showed activity. Initially, the antioxidant activity of the avenanthramides decreased in a similar order as for the corresponding cinnamic acids, that is: sinapic > caffeic > ferulic > p-coumaric acid. The avenanthramides derived from 2 were usually slightly more active than those derived from 1. All avenanthramides inhibited azo-initiated peroxidation of linoleic acid. 1c and 1s were initially the most effective compounds. The relative order of antioxidant activities was slightly different for the DPPH and the linoleic acid assays run in methanol and chlorobenzene, respectively.