115663-19-9

Upstream product

• 103781-89-1 6-benzyloxy-1H-indole-2-carboxylic acid methyl ester 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 103763-39-9 4,5-dihydro-3-(6-benzyloxyindol-2-ylcarbonyl)furan-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 115663-20-2 1-(6-benzyloxyindol-2-yl)-4-hydroxy-2-methylbutan-1-one 

Relevant academic research and scientific papers

A NEW ROUTE TO 1-OXYGENATED CARBAZOLES. SYNTHESIS OF THE CARBAZOLE ALKALOIDS MURRAYAFOLINE-A AND MURRAYAQUINONE-A

1-Oxygenated carbazoles are prepared in 4 steps from indole-2-carboxylates by condensation with γ-butyrolactones to give the lactones (12), followed by hydrolysis with concomitant decarboxylation to the alcohols (13), and oxidation to the aldehydes (14).The aldehydes (14) cyclise to 1-methoxycarbazoles on treatment with boron trifluoride-methanol or with methanolic hydrogen chloride.The methoxycarbazoles (15a) and (4) were converted into the corresponding carbazolequinones (18) and (7) by demethylation, and oxidation.The carbazole alkaloids murrayafoline-A (4) and murrayaquinone-A (7) were prepared.