115665-83-3Relevant academic research and scientific papers
First palladium-catalyzed Heck reactions with efficient colloidal catalyst systems
Beller, Matthias,Fischer, Hartmut,Kuehlein, Klaus,Reisinger,Herrmann
, p. 257 - 259 (1996)
For the first time it has been shown that palladium colloids are effective and active catalysts for the olefination of aryl bromides (Heck reaction). Worthy of note are the high activities of the catalyst system for activated aryl bromides under optimized reaction conditions, which are better than or comparable with classical palladium phosphine complexes. Addition of phosphines strongly retards the reaction rate of the colloid catalyst. Nevertheless, this type of catalyst is not suitable for the activation of non-activated substrates, especially technically interesting aryl chlorides.
Carbon-carbon cross-coupling reactions under continuous flow conditions using poly(vinylpyridine) doped with palladium
Mennecke, Klaas,Solodenko, Wladimir,Kirschning, Andreas
experimental part, p. 1589 - 1599 (2009/04/03)
Coordinative immobilization of an oxime-based pallada-cycle to poly(vinylpyridine)/glass composite materials shaped as Raschig rings or placed within the PASSflow microreactor affords technical devices that are well suited for performing palladium-catalyzed carbon-carbon cross-coupling reactions in the flow-through mode. Reusability of the immobilized precatalyst as well as applications in the microwave field were investigated. Experiments with thiol- and pyridine-based scavengers were carried out, which revealed that the active palladium species is likely to be composed of nanoparticles of unknown nature and that the poly(vinylpyridine) carrier has scavenging properties for these particles. Georg Thieme Verlag Stuttgart.
