1156766-40-3

Upstream product

• 15570-12-4 3-methoxybenzenethiol 
• 6096-83-9 2?bromo?1?(3?bromo?4?methoxyphenyl)ethan?1?one 
• 35310-75-9 3-bromo-4-methoxyacetophenone 

Downstream Products

• 1649501-82-5 (3-bromo-4-methoxyphenyl)(6-methoxybenzo[b]thiophen-2-yl)methanone 
• 1649501-97-2 (Z)-1-(3-bromo-4-methoxyphenyl)-2-(3-methoxyphenylthio)-3-(dimethylamino)prop-2-en-1-one 

Relevant academic research and scientific papers

Efficient synthetic approach to substituted benzo[b]furans and benzo[b]thiophenes by iodine-promoted cyclization of enaminones

An efficient synthetic approach to the substituted benzo[b]furan and benzo[b]thiophene scaffolds by iodine-mediated cyclization of the corresponding enaminones is described. This protocol was applied to a large series of these latter precursors to afford the respective benzoheterocycles substituted at the C-2 position by a carbonyl group functionality. A study of the factors that control this process reveals that the reactivity depends on the presence of electron-donor groups in the aryl ring of the aryloxycarbonylic and arylthiocarbonylic moieties.