115679-07-7Relevant academic research and scientific papers
Alkylation and Aldol Reactions of Aldoxime Anions
Hassner, Alfred,Naeumann, Fritz
, p. 1823 - 1826 (2007/10/02)
The reaction of Z aldoximes with BuLi to give dianions and the properties of the latter were examined.D-Labelling and silylation confirm previous findings that only the Z isomer forms the dianion.Z-Hexanal oxime and Z-octanal oxime were deprotonated with BuLi, and the anions underwent aldol condensation reactions with several aldehydes and ketones including α, β-unsaturated aldehydes.Attempts to alkylate monoanions of OTHP ethers of aldoximes failed.However, carbanion addition to the C=N bond of some oxime OTHP ethers was observed.
