115723-78-9

Basic information

• Product Name: threo-3-bromo-2-hydroxy-3-phenyl-propionic acid methyl ester
• CAS NO: 115723-78-9
• Molecular Weight: 259.1
• Mol File: 115723-78-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: threo-3-bromo-2-hydroxy-3-phenyl-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: threo-3-bromo-2-hydroxy-3-phenyl-propionic acid methyl ester(115723-78-9)
• EPA Substance Registry System: threo-3-bromo-2-hydroxy-3-phenyl-propionic acid methyl ester(115723-78-9)

Safety Data

• Hazardous Substances Data: 115723-78-9(Hazardous Substances Data)

Upstream product

• 19190-80-8 methyl trans-3-phenylglycidate 
• 19190-80-8 cis-methyl 2,3-epoxy-3-phenylpropanoate 

Downstream Products

• 19190-80-8 cis-methyl 2,3-epoxy-3-phenylpropanoate 

Relevant articles and documents

Process for the preparation of (2r,3s)-3-phenylisoserine methyl ester acetate salt

A process for the enantioselective preparation of (2R,3S)-3-phenylisoserine methyl ester acetate salt of formula (I) which is an useful building block for the synthesis of taxane derivatives. The process involves the resolution of racemic threo-phenylisoserine amide and its conversion into (I).

Selective Additions of Gaseous Hydrochloric Acid to Crystalline Epoxides und Steroid-Epoxides

Solid epoxides add gaseous HCl or KBr regioselectively and without melting, if the melting points are sufficiently high.Such additions proceed diastereoselectively with chiral epoxides.These gas/solid reactions are compared to similar transformations in solution.One observes interesting reaction sequences in the conversions of steroidal epoxides.Thus the opening of the epoxide ring may be followed by cationic rearrangements, or it occurs elimination od water, if it creates conjugation to a carbonyl group.