115740-46-0Relevant academic research and scientific papers
A Study on the Mannich Reaction with 1,3-Indandione
Afsah, E. M.,Hammouda, M.,Khalifa, M. M.
, p. 1055 - 1058 (2007/10/02)
Attempted Mannich reaction with the title compound 1 using morpholine and formalin led to 2 or 4 according to the reaction conditions.Whereas, on using primary amines the diindeno pyridine (9-11) were obtained, in addition to 2-methylene-1,3-indandione (6), in case of 10 and 11. However, the Mannich bases 13-15 were formed on treating 2-benzylidene-1,3-indandione with the appropriate secondary amine.The structures 2,9-11 were confirmed via unambiguous syntheses.
