115754-95-5

Upstream product

• 115754-94-4 thiazol-2-ylmethyltriphenylphosphonium chloride 

Downstream Products

• 115754-97-7 3-phenyl-1-(2-thiazolyl)-(1E)-butene 
• 115754-96-6 3-methyl-1-(2-thiazolyl)-(1E)-butene 
• 138319-93-4 (4S,5S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-5-((E)-2-thiazol-2-yl-vinyl)-oxazolidine-3-carboxylic acid tert-butyl ester 
• 138319-93-4 (4R,5R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-5-((E)-2-thiazol-2-yl-vinyl)-oxazolidine-3-carboxylic acid tert-butyl ester 
• 115755-03-8 1-(4-methoxyphenyl)-2-(2-thiazolyl)-(E)-ethene 
• 84645-64-7 trans-2-(β-phenylvinyl)thiazole 
• 141873-74-7 (Z)-(3S,4R)-5-benzyloxy-3,4-O-isopropylidenedioxy-1-(2-thiazolyl)1-pentene 
• 141873-74-7 (E)-(3S,4R)-5-benzyloxy-3,4-O-isopropylidenedioxy-1-(2-thiazolyl)1-pentene 

Relevant academic research and scientific papers

Two-carbon chain extension of chiral aldehydes via 2-alkenylthiazoles: Synthesis of γ-functionalized alkanals

The reaction of 2-thiazolylmethylenetriphenylphosphorane (1a) in benzene with various aldehydes gives 2-alkenylthiazoles in variable E/Z ratios. Application of the thiazole-to-formyl deblocking protocol to the mixture of the olefins leads to saturated ald

THIAZOLYLMETHYLENETRIPHENYLPHOSPHORANE AND ITS BENZO DERIVATIVE: STABLE AND PRACTICAL WITTIG REAGENTS FOR THE SYNTHESIS OF VINYLTHIAZOLES AND VINYLBENZOTHIAZOLES. TWO-CARBON HOMOLOGATION OF ALDEHYDES.

The title thiazolyl phosphorane is a stable yet quite reactive Wittig-type reagent which uppon reaction with various aldehydes affords vinylthiazoles, mainly or exclusively as E-isomers, in very good yields.Also the benzothiazolyl phosphorane derivative, unlike a literature report, prove to react with aldehydes.Vinylthyazoles subjected to formyl deblocking from thiazole nucleous afford two-carbon homologated satured aldehydes.As an example, one of these vinylthiazoles, viz. the β-phenyl derivative 8f, proves to add n-butyl lithium cuprate to give after the formyl deblocking 3-phenylheptanal.