1158-20-9

Basic information

• Product Name: 1-(3,4-dihydroxy-phenyl)-dodecan-1-one
• Synonyms: 1-(3,4-dihydroxy-phenyl)-dodecan-1-one
• CAS NO: 1158-20-9
• Molecular Weight: 292.419
• Mol File: 1158-20-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3,4-dihydroxy-phenyl)-dodecan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-dihydroxy-phenyl)-dodecan-1-one(1158-20-9)
• EPA Substance Registry System: 1-(3,4-dihydroxy-phenyl)-dodecan-1-one(1158-20-9)

Safety Data

• Hazardous Substances Data: 1158-20-9(Hazardous Substances Data)

Upstream product

• 143-07-7 lauric acid 
• 120-80-9 benzene-1,2-diol 
• 112-16-3 n-dodecanoyl chloride 

Downstream Products

• 1155-60-8 4-dodecyl-1,2-benzenediol 

Relevant articles and documents

Selective acylation of phenols in boron trifluoride diethyl etherate solution and the mechanistic implication

In the presence of boron trifluoride diethyl etherate (BF3 · OEt2), direct acylation of phenols with free carboxylic acid is chemoselective and regioselective and no demethylation, if any, was observed. The para-directing effect of BF3·OEt2 is attributed to the large steric hindrance of the boron trifluoride-phenolic hydroxyl group complex, which blocks the ortho-acylation from occurrence. Microwave irradiation could not change the regioselectivity of BF3·OEt2 except the reaction time being greatly shortened.