115848-68-5Relevant articles and documents
Synthesis of Some New &β-Lactams, 4-Thiazolidinones and Pyrazolines
Fahmy, A. M.,Hassan, Kh. M.,Khalaf, A. A.,Ahmed, R. A.
, p. 884 - 887 (2007/10/02)
N-Arylidene-p-aminoacetophenone (I) and N-arylidene-4'-aminochalcones (V) have been converted into a series of substituted β-lactams (III) and 4-thiazolidinones (IV), and pyrazolines (VI, VII) respectively. p-Chloroacetamidoacetophenone (II) has also been converted into series of substituted 4'-piperidino/morpholinoacetoamidochalcones (X) which undergo cyclization on treatment with hydrazine, phenylhydrazine or thiourea to pyrazolines (XI, XII) and pyrimidine-2-thiones (XIII) respectively.The antibacterial and antifungal activities of the compounds have been determined.