1158503-82-2 Usage
Uses
Used in Pharmaceutical Industry:
Methyl 7-bromo-1H-indole-2-carboxylate is used as a reagent for the preparation of novel 2-aminopyridines, which are important building blocks in the synthesis of various pharmaceutical compounds. These 2-aminopyridines can be further modified and utilized in the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, Methyl 7-bromo-1H-indole-2-carboxylate serves as a valuable intermediate for the synthesis of a wide range of organic molecules. Its unique structural features make it a versatile compound for exploring new chemical reactions and developing innovative synthetic routes.
Used in Material Science:
The compound may also find applications in material science, particularly in the development of novel materials with specific properties. The indole moiety in Methyl 7-bromo-1H-indole-2-carboxylate can be exploited to design and synthesize new materials with potential applications in various industries, such as electronics, optics, and energy storage.
Check Digit Verification of cas no
The CAS Registry Mumber 1158503-82-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,8,5,0 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1158503-82:
(9*1)+(8*1)+(7*5)+(6*8)+(5*5)+(4*0)+(3*3)+(2*8)+(1*2)=152
152 % 10 = 2
So 1158503-82-2 is a valid CAS Registry Number.
1158503-82-2Relevant academic research and scientific papers
NOVEL 2-AMINO-PYRIDINE AND 2-AMINO-PYRIMIDINE DERIVATIVES AND MEDICINAL USE THEREOF
-
Paragraph 0406, (2017/03/14)
Provided is a compound superior in an autotaxin inhibitory action and the like, effective as a prophylactic or therapeutic drug for diseases involving ATX. The present invention relates to a compound represented by the following formula (I): [wherein each symbol is as described in the DESCRIPTION], which has a superior autotaxin inhibitory action and is useful as a prophylactic or therapeutic drug for diseases involving ATX.
Extending the versatility of the Hemetsberger-Knittel indole synthesis through microwave and flow chemistry
Ranasinghe, Nadeesha,Jones, Graham B.
, p. 1740 - 1742 (2013/04/10)
Microwave, flow and combination methodologies have been applied to the synthesis of a number of substituted indoles. Based on the Hemetsberger-Knittel (HK) process, modifications allow formation of products rapidly and in high yield. Adapting the methodology allows formation of 2-unsubstituted indoles and derivatives, and a route to analogs of the antitumor agent PLX-4032 is demonstrated. The utility of the HK substrates is further demonstrated through bioconjugation and subsequent ring closure and via Huisgen type [3+2] cycloaddition chemistry, allowing formation of peptide adducts which can be subsequently labeled with fluorine tags.
