115859-13-7

Basic information

• Product Name: 1(4H)-Pyridinecarboxylic acid, 4-[4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl]-, ethyl ester
• CAS NO: 115859-13-7
• Molecular Formula: C19H20FN3O2S
• Molecular Weight: 373.451
• Mol File: 115859-13-7.mol

Chemical Properties

• CAS DataBase Reference: 1(4H)-Pyridinecarboxylic acid, 4-[4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1(4H)-Pyridinecarboxylic acid, 4-[4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl]-, ethyl ester(115859-13-7)
• EPA Substance Registry System: 1(4H)-Pyridinecarboxylic acid, 4-[4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl]-, ethyl ester(115859-13-7)

Safety Data

• Hazardous Substances Data: 115859-13-7(Hazardous Substances Data)

Upstream product

• 93103-15-2 4-(4-fluorophenyl)-1,3-dihydro-2H-imidazole-2-thione 
• 456-00-8 2-amino-4'-fluoroacetophenone hydrochloride 
• 110-86-1 pyridine 
• 541-41-3 chloroformic acid ethyl ester 
• 115889-90-2 4-(4-fluorophenyl)-1-methyl-2-(methylsulfanyl)-1H-imidazole 

Relevant articles and documents

Synthetic and Mechanistic Studies on the Preparation of Pyridyl-Substituted Imidazothiazoles

A new method is presented for the introduction of the 4'-pyridyl substituent into 6-aryl-2,3-dihydroimidazothiazoles.The method involves treatment of the imidazothiazolines with the reactive complex of pyridine and ethyl chloroformate and oxidative deethyl carboxylation of the dihydropyridine adducts formed.Sulfur in refluxing mesitylene was found most suitable for the latter reaction, but chromium trioxide in pyridine or KtBuO and air were also effective.