1158680-87-5 Usage
General Description
Ethanone, 1-(7-bromo-1H-indazol-1-yl)- is a chemical compound with the molecular formula C10H8BrN3O. It is a derivative of indazole, a bicyclic heterocyclic compound containing a five-membered ring fused to a six-membered ring. The presence of the bromine substituent gives this compound unique chemical properties and potential applications in pharmaceutical research and development. Ethanone, 1-(7-bromo-1H-indazol-1-yl)- may be used as a building block for the synthesis of novel drugs or as a pharmaceutical intermediate in the production of other chemicals. Its structure and reactivity make it an interesting target for further investigation in the field of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 1158680-87-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,8,6,8 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1158680-87:
(9*1)+(8*1)+(7*5)+(6*8)+(5*6)+(4*8)+(3*0)+(2*8)+(1*7)=185
185 % 10 = 5
So 1158680-87-5 is a valid CAS Registry Number.
InChI:InChI=1S/C9H7BrN2O/c1-6(13)12-9-7(5-11-12)3-2-4-8(9)10/h2-5H,1H3
1158680-87-5Relevant articles and documents
Protected indazole boronic acid pinacolyl esters: Facile syntheses and studies of reactivities in Suzuki-Miyaura cross-coupling and hydroxydeboronation reactions
Crestey, Fran?ois,Lohou, Elodie,Stiebing, Silvia,Collot, Valérie,Rault, Sylvain
body text, p. 615 - 619 (2009/07/09)
The paper describes a rapid and efficient synthesis for the isolation of protected indazolylboronic esters. These compounds were synthesized by reaction between prepared protected haloindazoles and bis(pinacolato)diboron. The effects of solvent, temperature, reaction time, and the nature of halogen atom as well as protecting group were investigated. Additionaly, these compounds reacted either with aryl halides in a Suzuki-Miyaura cross-coupling reaction or with hydrogen peroxide in a hydroxydeboronation reaction showing the potential access to new aryl and hydroxyindazole libraries. Georg Thieme Verlag Stuttgart.
