115875-99-5Relevant academic research and scientific papers
Consice Synthesis of CC-1065/Duocarmycin Pharmacophore Using the Intramolecular Heck Reaction
Sakamoto, Takao,Kondo, Yoshinori,Uchiyama, Masanobu,Yamanaka, Hiroshi
, p. 1941 - 1942 (2007/10/02)
3-Methyleneindoline derivatives were synthesized by intramolecular Heck reaction of N-allyl-2-iodoaniline derivatives in the presence of Ag2CO3.This method was successfully applied to the synthesis of the CC-1065/duocarmycin pharmacophore.
