115888-85-2

Basic information

• Product Name: (+/-)-latifine dimethyl ether
• Synonyms: (+/-)-latifine dimethyl ether
• CAS NO: 115888-85-2
• Molecular Weight: 313.397
• Mol File: 115888-85-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (+/-)-latifine dimethyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-latifine dimethyl ether(115888-85-2)
• EPA Substance Registry System: (+/-)-latifine dimethyl ether(115888-85-2)

Safety Data

• Hazardous Substances Data: 115888-85-2(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 1198184-60-9 2-(2,3-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanamine 
• 140843-31-8 3,4-dimethoxy-2-iodo-N-methylbenzylamine 
• 140843-32-9 2-bromo-3,4-dimethoxy-N-methylbenzylamine 
• 55171-60-3 2-bromo-3,4-dimethoxybenzylaldehyde 
• 57193-17-6 4,4-dimethyl-2-(3,4-dimethoxyphenyl)-2-oxazoline 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 93-07-2 Veratric acid 
• 115802-62-5 4,5-dihydro-2-<3,4-dimethoxy-2-(4'-methoxybenzyl)phenyl>-4,4-dimethyloxazole 
• 115802-59-0 N-methyl-3,4-dimethoxy-2-(4'-methoxybenzyl)benzamide 
• 2746-25-0 p-Methoxybenzyl bromide 
• 115802-58-9 3,4-dimethoxy-2-(4'-methoxybenzyl)benzoic acid 
• 117671-67-7 4,5-dimethoxy-3-(4'-methoxyphenyl)phthalide 
• 1522-67-4 N-phenyl-3,4-dimethoxybenzamide 

Relevant articles and documents

Efficient syntheses of (±)-cherylline and latifine dimethyl ether

A concise route for the syntheses of (±)-cherylline and latifine dimethyl ether is reported. The key steps involved are Michael addition of veratrole with p-methoxy nitrostyrene (for cherylline), anisole with 2,3-dimethoxy nitrostyrene (for latifine), and reduction of nitro intermediate, followed by Pictet-Spengler cyclization. Copyright

A convenient synthesis of 4-substituted 1,2,3,4-tetrahydroisoquinolin-4-ols by a novel intramolecular Barbier reaction and by an insertion reaction: Reaction scope and limitations

4-Substituted 1,2,3,4-tetrahydroisoquinolin-4-ols were prepared from N-(2-iodobenzyl)phenacylamines by an intramolecular Barbier reaction with butyllithium and by an insertion reaction with zerovalent nickel. The scope and limitations of these reactions were discussed.

An Efficient Synthesis of (+/-)-Latifine Dimethyl Ether

4,5-Dimethoxy-3-(4'-methoxyphenyl)phthalide (2) was hydrogenolysed to give 3,4-dimethoxy-2-(4'-methoxybenzyl)benzoic acid (3).The N-methylamide of (3) was lithiated and treated with dimethylformamide to furnish 3,4-dihydro-3-hydroxy-5,6-dimethoxy-4-(4'-me