115888-85-2

Upstream product

• 115831-71-5 3,4-dihydro-3-hydroxy-5,6-dimethoxy-4-(4'-methoxyphenyl)-2-methylisoquinolin-1(2H)-one 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 50-00-0 formaldehyd 
• 1198184-60-9 2-(2,3-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanamine 
• 140843-31-8 3,4-dimethoxy-2-iodo-N-methylbenzylamine 
• 140843-32-9 2-bromo-3,4-dimethoxy-N-methylbenzylamine 
• 131326-77-7 2-[(2-Iodo-3,4-dimethoxy-benzyl)-methyl-amino]-1-(4-methoxy-phenyl)-ethanone 
• 131326-84-6 2-[(2-Bromo-3,4-dimethoxy-benzyl)-methyl-amino]-1-(4-methoxy-phenyl)-ethanone 
• 138490-95-6 2-iodo-3,4-dimethoxybenzaldehyde 
• 55171-60-3 2-bromo-3,4-dimethoxybenzylaldehyde 
• 57193-17-6 4,4-dimethyl-2-(3,4-dimethoxyphenyl)-2-oxazoline 
• 93-07-2 Veratric acid 
• 115802-62-5 4,5-dihydro-2-<3,4-dimethoxy-2-(4'-methoxybenzyl)phenyl>-4,4-dimethyloxazole 
• 115802-59-0 N-methyl-3,4-dimethoxy-2-(4'-methoxybenzyl)benzamide 

Relevant academic research and scientific papers

Efficient syntheses of (±)-cherylline and latifine dimethyl ether

A concise route for the syntheses of (±)-cherylline and latifine dimethyl ether is reported. The key steps involved are Michael addition of veratrole with p-methoxy nitrostyrene (for cherylline), anisole with 2,3-dimethoxy nitrostyrene (for latifine), and reduction of nitro intermediate, followed by Pictet-Spengler cyclization. Copyright

Convenient synthesis of amaryllidaceae alkaloid, (+/-) latifine dimethyl ether

A short route for the synthesis of (+/-) latifine dimethyl ether is reported. The key steps involved are Grignard reaction, conversion of alcohol to nitrile using trimethylsilyl cyanide, reduction of the nitrile intermediate followed by Pictet-Spengler cy

A convenient synthesis of 4-substituted 1,2,3,4-tetrahydroisoquinolin-4-ols by a novel intramolecular Barbier reaction and by an insertion reaction: Reaction scope and limitations

4-Substituted 1,2,3,4-tetrahydroisoquinolin-4-ols were prepared from N-(2-iodobenzyl)phenacylamines by an intramolecular Barbier reaction with butyllithium and by an insertion reaction with zerovalent nickel. The scope and limitations of these reactions were discussed.

A NEW INTRAMOLECULAR BARBIER REACTION OF N-(2-IODOBENZYL)PHENACYLAMINES: A CONVENIENT SYNTHESIS OF 1,2,3,4-TETRAHYDROISOQUINOLIN-4-OLS

4-Phenyl-1,2,3,4-tetrahydroisoquinolin-4-ols were prepared by an intramolecular Barbier reaction of N-(2-iodobenzyl)phenacylamines with butyllithium in good yields.

An Efficient Synthesis of (+/-)-Latifine Dimethyl Ether

4,5-Dimethoxy-3-(4'-methoxyphenyl)phthalide (2) was hydrogenolysed to give 3,4-dimethoxy-2-(4'-methoxybenzyl)benzoic acid (3).The N-methylamide of (3) was lithiated and treated with dimethylformamide to furnish 3,4-dihydro-3-hydroxy-5,6-dimethoxy-4-(4'-me