1158948-04-9

Basic information

• Product Name: 2,3,4-tribromo-5-(3,5-difluoro-2-hydroxyphenyl)-1H-pyrrole
• Synonyms: 2,3,4-tribromo-5-(3,5-difluoro-2-hydroxyphenyl)-1H-pyrrole
• CAS NO: 1158948-04-9
• Molecular Weight: 431.857
• Mol File: 1158948-04-9.mol

Chemical Properties

• CAS DataBase Reference: 2,3,4-tribromo-5-(3,5-difluoro-2-hydroxyphenyl)-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-tribromo-5-(3,5-difluoro-2-hydroxyphenyl)-1H-pyrrole(1158948-04-9)
• EPA Substance Registry System: 2,3,4-tribromo-5-(3,5-difluoro-2-hydroxyphenyl)-1H-pyrrole(1158948-04-9)

Safety Data

• Hazardous Substances Data: 1158948-04-9(Hazardous Substances Data)

Upstream product

• 1158948-10-7 2,3,4-tribromo-5-(3,5-difluoro-2-methoxyphenyl)-1H-pyrrole 
• 131782-50-8 3,5-difluoro-2-methoxybenzaldehyde 
• 1198777-67-1 2-(3,5-difluoro-2-methoxyphenyl)-1-(p-tolylsulfonyl)-2,3-dihydro-1H-pyrrole 
• 1198777-64-8 N-[1-(3,5-difluoro-2-methoxyphenyl)-but-3-ynyl]-4-methylbenzene-sulfonamide 
• 1198777-60-4 N-[1-(3,5-difluoro-2-methoxyphenyl)-4-(trimethylsilyl)but-3-ynyl]-4-methylbenzenesulfonamide 
• 1198777-57-9 N-(3,5-difluoro-2-methoxybenzylidene)-4-methylbenzenesulfonamide 
• 1198777-68-2 2-(3,5-difluoro-2-methoxyphenyl)-1H-pyrrole 

Relevant articles and documents

Silver(I)-catalyzed route to pyrroles: Synthesis of halogenated pseudilins as allosteric inhibitors for myosin atpase and x-ray crystal structures of the protein-inhibitor complexes

The pentahalogenated 2-arylpyrrole-type alkaloids pentabromopseudilin and pentachloropseudilin represent a new class of isoform-specific allosteric inhibitors of myosin ATPase. Herein, we describe an application of the silver(I)-catalyzed cycloisomerizati

MEANS FOR TREATING MYOSIN-RELATED DISEASES

The present invention provides a method of designing a modulator of a myosin, the method comprising molecular modeling of a compound such that the modeled compound interacts with at least three amino acid residues of said myosin, said residues being selec

Total synthesis of pentabromo- and pentachloropseudilin, and synthetic analogues-allosteric inhibitors of myosin ATPase

Stopping myo: The total syntheses of the title compounds have been achieved using a highly efficient silver(I)- catalyzed cyclization of N-tosyl-homopropargylamines. The pseudilin derivatives represent a novel class of myosin inhibitors. A new allosteric