1158968-99-0Relevant academic research and scientific papers
Iodocyclization of n-arylpropynamides mediated by hypervalent iodine reagent: Divergent synthesis of iodinated quinolin-2-ones and spiro[4,5]trienones
Zhou, Ying,Zhang, Xiang,Zhang, Yong,Ruan, Linxin,Zhang, Jiacheng,Zhang-Negrerie, Daisy,Du, Yunfei
, p. 150 - 153 (2017)
PhI(OCOCF3)2 acts as both a nonmetal oxidant and an iodination reagent to trigger iodocyclization of N-arylpropynamides while selectively affording iodinated quinolin-2-ones or the spiro[4,5]trienone skeleton, depending on the substituent pattern. In cases where the Narylpropynamide bears a para-fluorine on the aniline ring, the spiro compound is formed via an exclusive defluorination process; otherwise, the product was quinolin-2-one.
Iodocyclization of N-aryl-3-phenylpropiolamides by I2/CAN: A convenient route for the selective synthesis of quinolin-2-ones
Likhar, Pravin R.,Racharlawar, Shailesh S.,Karkhelikar, Manjusha V.,Subhas,Sridhar
experimental part, p. 2407 - 2414 (2011/09/19)
A general method has been developed for the selective synthesis of 3-iodoquinolin-2-ones and spiro[4.5]trienes via intramolecular iodocyclization of N-(ortho-substituted aryl)-3-phenylpropiolamides using iodine/cerium(IV) ammonium nitrate reagent under mi
Electrophilic ipso-halocyclization of N-arylpropynamides with polyfluoroalkyl alcohols: Selective synthesis of 8-(polyfluoroalkoxy)azaspiro[4. 5]trienes
Wang, Zhi-Qiang,Tang, Bo-Xiao,Zhang, Hong-Ping,Wang, Feng,Li, Jin-Heng
experimental part, p. 891 - 902 (2009/10/14)
A novel and efficient method for the synthesis of 8-(polyfluoroalkoxy)-1- azaspiro[4.5]deca-3,6,9-trien-2-ones has been demonstrated via the electrophilic ipso-halocyclization of Narylpropynamides with polyfluoroalkyl alcohols. In the presence of N-halosu
