1158984-95-2

Basic information

• Product Name: 1-(Phenylsulfonyl)indole-2-boronic acid MIDA ester, 1-(Phenylsulfonyl)indole-2-boronic acid, Methyliminodiacetic acid anhydride
• Synonyms: 1-(Phenylsulfonyl)-2-indolylboronic acid MIDA ester;1-(Phenylsulfonyl)indole-2-boronic acid MIDA ester, 1-(Phenylsulfonyl)indole-2-boronic acid, Methyliminodiacetic acid anhydride;1-(Phenylsulfonyl)indole-2-boronic acid MIDA ester;1-(Phenylsulfonyl)indole-3-boronic acid MIDA ester;1-(Phenylsulfonyl)-2-indolylboronic acid MIDA ester 96%
• CAS NO: 1158984-95-2
• Molecular Formula: C₁₉H₁₇BN₂O₆S
• Molecular Weight: 412.22408
• Mol File: 1158984-95-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 159-165 °C
• Appearance: /
• CAS DataBase Reference: 1-(Phenylsulfonyl)indole-2-boronic acid MIDA ester, 1-(Phenylsulfonyl)indole-2-boronic acid, Methyliminodiacetic acid anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Phenylsulfonyl)indole-2-boronic acid MIDA ester, 1-(Phenylsulfonyl)indole-2-boronic acid, Methyliminodiacetic acid anhydride(1158984-95-2)
• EPA Substance Registry System: 1-(Phenylsulfonyl)indole-2-boronic acid MIDA ester, 1-(Phenylsulfonyl)indole-2-boronic acid, Methyliminodiacetic acid anhydride(1158984-95-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1158984-95-2(Hazardous Substances Data)

Usage

Uses

MIDA boronate for slow-release cross-couplingMIDA boronates as stable boronic acid surrogates for classically challenging cross-couplings.Suzuki Cross-Coupling with MIDA Boronates

Upstream product

• 4408-64-4 N-methyliminodiacetic acid 

Downstream Products

• 1158985-11-5 N-phenylsulfonyl-2-(2,3-dimethoxyphenyl)indole 
• 1158985-06-8 N-phenylsulfonyl-2-(4-tert-butoxyphenyl)indole 

Relevant articles and documents

SLOW RELEASE OF ORGANOBORONIC ACIDS IN CROSS-COUPLING REACTIONS

A method of performing a chemical reaction includes reacting a compound selected from the group consisting of an organohalide and an organo-pseudohalide, and a protected organoboronic acid represented by formula (I) in a reaction mixture: R1-B-T; where R1 represents an organic group, T represents a conformationalIy rigid protecting group, and B represents boron having sp3 hybridization. When unprotected, the corresponding organoboronic acid is unstable by the boronic acid neat stability test. The reaction mixture further includes a base having a pKB of at least 1 and a pal ladium catalyst. The method further includes forming a cross-coupled product in the reaction mixture.