1158984-95-2 Usage
Uses
Used in Pharmaceutical Industry:
1-(Phenylsulfonyl)indole-2-boronic acid MIDA ester, 1-(Phenylsulfonyl)indole-2-boronic acid, and Methyliminodiacetic acid anhydride are used as intermediates for the synthesis of various pharmaceutical compounds. Their unique reactivity and stability make them suitable for the development of new drugs and drug candidates.
Used in Chemical Research:
In the field of chemical research, these compounds are used as stable boronic acid surrogates for classically challenging cross-couplings. Their ability to form stable boronate esters allows for the development of new synthetic routes and the exploration of novel chemical reactions.
Used in Suzuki Cross-Coupling:
1-(Phenylsulfonyl)indole-2-boronic acid MIDA ester, 1-(Phenylsulfonyl)indole-2-boronic acid, and Methyliminodiacetic acid anhydride are utilized in Suzuki cross-coupling reactions, a widely used method for the formation of carbon-carbon bonds in organic synthesis. Their application in this process enables the creation of a diverse range of molecular structures with potential applications in various industries, including pharmaceuticals, materials science, and agrochemistry.
Used in Slow-Release Cross-Coupling:
These compounds are also employed in the development of slow-release cross-coupling systems, which can provide controlled release of active ingredients in various applications, such as drug delivery and agrochemical formulations. This controlled release can help improve the efficacy and safety of the final product by reducing the potential for side effects and environmental impact.
Check Digit Verification of cas no
The CAS Registry Mumber 1158984-95-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,8,9,8 and 4 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1158984-95:
(9*1)+(8*1)+(7*5)+(6*8)+(5*9)+(4*8)+(3*4)+(2*9)+(1*5)=212
212 % 10 = 2
So 1158984-95-2 is a valid CAS Registry Number.
1158984-95-2Relevant academic research and scientific papers
SLOW RELEASE OF ORGANOBORONIC ACIDS IN CROSS-COUPLING REACTIONS
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Page/Page column 35-36, (2010/04/27)
A method of performing a chemical reaction includes reacting a compound selected from the group consisting of an organohalide and an organo-pseudohalide, and a protected organoboronic acid represented by formula (I) in a reaction mixture: R1-B-T; where R1 represents an organic group, T represents a conformationalIy rigid protecting group, and B represents boron having sp3 hybridization. When unprotected, the corresponding organoboronic acid is unstable by the boronic acid neat stability test. The reaction mixture further includes a base having a pKB of at least 1 and a pal ladium catalyst. The method further includes forming a cross-coupled product in the reaction mixture.
