115901-59-2

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 110-91-8 morpholine 
• 1080-44-0 N-Tosylglycine 
• 56218-62-3 2-(4-methylphenylsulfonamido)acetyl chloride 

Downstream Products

• 115901-73-0 [(2R,3S)-3-Hydroxy-3-phenyl-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-morpholin-4-yl-methanone 
• 115901-66-1 4-Methyl-N-(2-morpholin-4-yl-2-oxo-ethyl)-N-(3-oxo-3-phenyl-propyl)-benzenesulfonamide 

Relevant academic research and scientific papers

IMPROVED PROCESS FOR THE PREPARATION OF ROXADUSTAT

A synthetic route for the preparation of Roxadustat, or a pharmaceutically acceptable salt thereof. Each route involves several novel intermediates and avoids the use of column chromatography.

Juvenile hormone like substances: Part XV - Synthesis and biological activities of some juvenile hormone analogues containing sulphonamide feature

A large number of juvenile hormone analogues 4-19 containing sulphonamide feature have been synthesized. Preliminary biological screening of one representative, N-(2-oxo-2-piperidino-ethyl) benzenesulphonamide 16a reveals a positive juvenile hormonal activity and chemosterilizing effect against potato tuber moth Phthorimaea operculella.