1159094-84-4

Upstream product

• 1080-06-4 L-Tyr-OMe 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 1158962-48-1 (S)-2-amino-1-(4-benzyloxyphenyl)-3-ethylpentan-3-ol 
• 1158962-49-2 (S)-1-(4-(4-methoxybenzyloxy)phenyl)-2-amino-3-ethylpentan-3-ol 
• 1218924-66-3 (S)-1-(4-(4-vinylbenzyloxy) phenyl)-2-amino-3-ethylpentan-3-ol 

Relevant academic research and scientific papers

Enantioselective addition of phenylacetylene to aldehydes catalyzed by polymer-supported titanium(IV) complexes of β-hydroxy amides

A series of polymer-supported chiral β-hydroxy amides and C 2-symmetric β-hydroxy amides have been synthesized and successfully used for the enantioselective addition of phenylacetylene to aldehydes. High yields (up to 93%) and enantioselectivities (up to 92% ee) were achieved by using polymer-supported chiral bhydroxy amide 4b. The resin 4b is reused four times, giving the product with enantioselectivity 80% ee. Fortunately, it is found that this heterogonous system is suitable not only for aromatic aldehydes but also aliphatic aldehyde.