115919-18-1Relevant articles and documents
One-pot gold-catalyzed synthesis of azepino[1,2-a]indoles
Cera, Gianpiero,Piscitelli, Stefano,Chiarucci, Michel,Fabrizi, Giancarlo,Goggiamani, Antonella,Ramón, Rubén S.,Nolan, Steven P.,Bandini, Marco
, p. 9891 - 9895 (2012)
Indoles from scratch: A gold(I)/N-heterocyclic carbene complex (IPr=1,3-di(isopropylphenyl)imidazol-2-ylidene) was found to be particularly effective as a catalyst, enabling the one-pot synthesis of tricyclic azepinoindoles by an unprecedented cascade reaction. Readily available substrates, high chemoselectivity, good yields, and water as the only stoichiometric by-product are some of the main advantages of this method. Copyright
Transition-Metal-Free Radical Hydrotrifluoromethylation of Alkynes
Matcha, Kiran,Antonchick, Andrey P.
supporting information, p. 309 - 312 (2019/01/24)
A combination of readily available and bench-stable CF3SO2Na and tBuOOH was efficiently used for hydrotrifluoromethylation of alkynes. An excellent trans-selectivity was demonstrated in the synthesis of alkenes. The developed mild reaction conditions allow the supression of the competing Meyer–Schuster-type rearrangement.
Bronsted acid mediated nitrogenation of propargylic alcohols: An efficient approach to alkenyl nitriles
Huang, Xiaoqiang,Jiao, Ning
, p. 4324 - 4328 (2014/06/23)
A novel and efficient approach to alkenyl nitriles from readily available propargylic alcohols has been developed. This nitrogenation reaction is transition-metal-free and could be conducted under air at ambient temperature, which makes this protocol promising and practical. Moreover, NH4Br is disclosed as an efficient additive to promote the stereoselectivity of this reaction. the Partner Organisations 2014.
