1159600-11-9

Basic information

• Product Name: 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester
• Synonyms: 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester
• CAS NO: 1159600-11-9
• Molecular Weight: 342.327
• Mol File: 1159600-11-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester(1159600-11-9)
• EPA Substance Registry System: 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester(1159600-11-9)

Safety Data

• Hazardous Substances Data: 1159600-11-9(Hazardous Substances Data)

Upstream product

• 456-48-4 3-Fluorobenzaldehyde 
• 917388-62-6 3-(3-fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid ethyl ester 
• 58606-42-1 N-hydroxy-3-fluoro-benzenecarboximidoyl chloride 
• 458-02-6 3-fluorobenzaldehyde oxime 
• 73781-91-6 6-Chloronicotinic acid methyl ester 
• 1159251-38-3 [3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-methanol 

Downstream Products

• 1159600-20-0 {6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridin-3-yl}-thiomorpholin-4-yl-methanone 
• 1159600-17-5 N-cyclopropyl-6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinamide 
• 1159600-14-2 N-cyclopropylmethyl-6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinamide 
• 1159600-12-0 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-N-(2,2,2-trifluoro-ethyl)-nicotinamide 
• 1159600-16-4 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF ISOXAZOLYL- METHOXY NICOTINIC ACIDS

The present invention relates to a process for the preparation of a compound of formula (I) wherein R1 and R2 are as defined herein, which is useful as an intermediate in the preparation of active pharmaceutical compounds.

ISOXAZOLE-PYRIDINE DERIVATIVES

The present invention is concerned with isoxazole-pyridine derivatives of formula I wherein X, R1 to R6 are as described herein. The compounds are active on the GABA A α5 receptor binding site and useful for the treatment of cognitive disorders, such as Alzheimer's disease.