458-02-6Relevant articles and documents
On the mixed oxides-supported niobium catalyst towards benzylamine oxidation
Granato, álisson Silva,de Carvalho, Gustavo S. Gon?alves,Fonseca, Carla G.,Adrio, Javier,Leit?o, Alexandre A.,Amarante, Giovanni Wilson
, p. 118 - 125 (2020/09/11)
A series of mixed oxides-supported niobium-based catalysts has been synthesized and applied towards oxidation reactions of benzylamine derivatives. Under the optimized reaction conditions, the selectivity to oxime enhanced, leading to the main product with up to 72 %. Moreover, even α-substituted benzylamines were well tolerated and led to oximes in good isolated yields. It is important to mention; four equivalents of the harmless and inexpensive hydrogen peroxide were employed as oxidizing agent. Mechanism hypothesis suggested that the reaction proceed to selective benzylamine oxidation into nitroso intermediate, following by formation of the corresponding oxime tautomer mediated by an unstable water produced by NbOx supported catalyst. This consists the first mixed oxides-supported niobium-based catalyst for selective oxidation of benzylamines to oximes.
Isoxazoline-pyrazole amide compound as well as preparation method and application thereof
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Paragraph 0108-0112, (2021/05/15)
The invention discloses an isoxazoline-pyrazole amide compound, which has the following structural formula (I) as shown in the specification. Each substituent group is shown in the specification. The invention also provides a preparation method and application of the compound. The compound provided by the invention is suitable for killing insects.
ISOXAZOLE DERIVATIVES AND PREPARATION PROCESS THEREOF
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Paragraph 114-116; 123-125, (2020/03/15)
The present invention relates to an isoxazole derivative compound of Formula (1) useful as a substance for treating respiratory viral infectious disease caused by coronavirus, in particular, Middle East respiratory syndrome-coronavirus (MERS-CoV); a pharm
