1159600-45-9

Upstream product

• 458-02-6 3-fluorobenzaldehyde oxime 
• 58606-42-1 N-hydroxy-3-fluoro-benzenecarboximidoyl chloride 
• 917388-62-6 3-(3-fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid ethyl ester 
• 73781-91-6 6-Chloronicotinic acid methyl ester 
• 127426-56-6 [3-(4-chloro-phenyl)-5-methyl-isoxazol-4-yl]-methanol 
• 97026-71-6 (3-(4-chlorophenyl)-5-methyl)isoxazole-4-carboxylic acid ethyl ester 
• 28123-63-9 4-chlorobenzohydroximoyl chloride 
• 3848-36-0 4-chlorobenzaldoxime 
• 104-88-1 4-chlorobenzaldehyde 
• 456-48-4 3-Fluorobenzaldehyde 
• 1159251-38-3 [3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-methanol 

Downstream Products

• 1159602-21-7 6-[3-(4-chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-N-(1-methyl-1H-pyrazol-4-yl)-nicotinamide 
• 1159600-46-0 6-[3-(4-chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid 
• 1159600-47-1 6-[3-(4-chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-N-(2,2,2-trifluoro-ethyl)-nicotinamide 
• 1159600-49-3 6-[3-(4-chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-N-cyclopropylmethyl-nicotinamide 

Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF ISOXAZOLYL- METHOXY NICOTINIC ACIDS

The present invention relates to a process for the preparation of a compound of formula (I) wherein R1 and R2 are as defined herein, which is useful as an intermediate in the preparation of active pharmaceutical compounds.

PROCESS FOR THE PREPARATION OF ISOXAZOLYL-METHOXY-NICOTINIC ACIDS

The present invention relates to a process for the preparation of a compound of formula (I) which is useful as an intermediate in the preparation of active pharmaceutical compounds from a compound of formula (IV) wherein R1 and R2 ar

ISOXAZOLE-PYRIDINE DERIVATIVES

The present invention is concerned with isoxazole-pyridine derivatives of formula I wherein X, R1 to R6 are as described herein. The compounds are active on the GABA A α5 receptor binding site and useful for the treatment of cognitive disorders, such as Alzheimer's disease.