1159609-95-6

Basic information

• Product Name: (1R,2S)-1-Amino-2-ethenyl-cyclopropanecarboxylic acid ethyl ester 4-methylbenzenesulfonate
• Synonyms: (1R,2S)-1-Amino-2-ethenyl-cyclopropanecarboxylic acid ethyl ester 4-methylbenzenesulfonate;Cyclopropanecarboxylic acid, 1-aMino-2-ethenyl-, ethyl ester, (1R,2S)-, 4-Methylbenzenesulfonate (1:1);(1R,2S)-1-aMino-2-ethenyl-cyclopropanecarboxylic acid ethyl ester tosylate;ethyl (1R,2S)-1-amino-2-vinylcyclopropane-1-carboxylate 4-methylbenzenesulfonate
• CAS NO: 1159609-95-6
• Molecular Formula: C₇H₈O₃S*C₈H₁₃NO₂
• Molecular Weight: 327.39594
• Mol File: 1159609-95-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 136-138℃
• Appearance: /
• CAS DataBase Reference: (1R,2S)-1-Amino-2-ethenyl-cyclopropanecarboxylic acid ethyl ester 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-1-Amino-2-ethenyl-cyclopropanecarboxylic acid ethyl ester 4-methylbenzenesulfonate(1159609-95-6)
• EPA Substance Registry System: (1R,2S)-1-Amino-2-ethenyl-cyclopropanecarboxylic acid ethyl ester 4-methylbenzenesulfonate(1159609-95-6)

Safety Data

• Hazardous Substances Data: 1159609-95-6(Hazardous Substances Data)

Usage

General Description

"(1R,2S)-1-Amino-2-ethenyl-cyclopropanecarboxylic acid ethyl ester 4-methylbenzenesulfonate" is a complex organic chemical compound. Its molecular structure consists of an amino group and an ethenyl group positioned on a cyclopropane ring, which is a three-carbon ring. This is attached to a carboxylic acid group that further forms an ester with an ethyl group. The 4-methylbenzenesulfonate moiety is a separate functional group that combines with the whole structure through ionic or coordinate bonds. The "(1R,2S)" prefix indicates the specific stereochemistry of the molecule, meaning that it has chiral centers making it optically active. Information regarding its properties, synthesis, and applications might be compound-specific and not readily available due to its complex structure.

Upstream product

• 104-15-4 toluene-4-sulfonic acid 
• 1225330-50-6 (1R,2S)-1-(E)-N-phenylmethyleneamino-2-vinylcyclopropanecarboxylic acid ethyl ester 

Downstream Products

• 862119-82-2 (2S,4R)-tert-butyl 2-((1R,2S)-1-(ethoxycarbonyl)-2-vinylcyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate 
• 960390-07-2 1,1-dimethylethyl (2S,4S)-2-[({(1R,2S)-2-ethenyl-1-[(ethyloxy)carbonyl]cyclopropyl}amino)carbonyl]-4-hydroxy-1-pyrrolidinecarboxylate 
• 746657-36-3 (1R,2S)-ethyl 1-amino-2-vinylcyclopropanecarboxylate 
• 259217-95-3 N-Boc-(1R,2S)-1-amino-2-vinylcyclopropane carboxylic acid ethyl ester 
• 1152134-45-6 (1R,2R)-1-(tert-butoxycarbonylamino)-2-(difluoromethyl)cyclopropanecarboxylic acid 
• 1108657-27-7 C₃₇H₄₆N₄O₆ 
• 1108657-04-0 C₃₆H₄₄N₄O₆ 

Relevant articles and documents

METHOD FOR PRODUCING 1-AMINO-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE

It is an object of the present invention to provide a novel method for producing (1R,2S)/(1S,2R)-1-amino-1-alkoxycarbonyl-2-vinylcyclopropane which is useful as a synthetic intermediate of therapeutic agents for hepatitis C and a synthetic intermediate thereof. According to the present invention, when a trans-2-butene derivative having a leaving group at each of the 1- and 4-positions is reacted with a malonic ester in the presence of a base, a specific amount of an alkali metal alkoxide or an alkali metal hydride is used as the base, and further a specific amount of a malonic ester is used to produce a cyclopropane diester, and further, chiral or achiral 1-amino-1-alkoxy-carbonyl-2-vinylcyclopropane and a salt thereof are synthesized using the cyclopropane diester.