1160170-23-9Relevant academic research and scientific papers
Iodine mediated intramolecular C2-amidative cyclization of indoles: A facile access to indole fused tetracycles
Badigenchala, Sindhura,Rajeshkumar, Venkatachalam,Sekar, Govindasamy
supporting information, p. 2297 - 2305 (2016/03/05)
A novel and metal-free I2-mediated intramolecular C2 amidation of indoles under mild reaction conditions is developed. This methodology affords various indole fused tetracyclic compounds, such as benzo[4,5]imidazo[1,2-a]indoles by intramolecular C2 amidation of N-aryl substituted indoles. This C2 sulfonamidative cyclization also offers convenient access to indolo[2,3-b]indoles and dihydroindolo[2,3-b]quinoline from C3 aryl substituted indoles in good to excellent yields. Indolo[2,3-b]quinolines are also synthesized by the domino cyclization-detosylation-aromatization reaction sequence.
One-Pot N-Arylation of indoles directly from N-arylsulfonylindoles via consecutive deprotection and SnAr reactions with activated aryl halides
Xu, Hui,Fan, Ling-Ling
experimental part, p. 321 - 323 (2009/11/30)
An efficient one-pot step by step t-BuOK-mediated procedure for the synthesis of N-arylindoles has been developed in moderate to good yields. The protocol involves the consecutive deprotection of N-arylsulfonylindoles as latent indoles and subsequent SnAr
