1160285-30-2

Basic information

• Product Name: N-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)-2-hydroxyacetamide
• Synonyms: N-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)-2-hydroxyacetamide
• CAS NO: 1160285-30-2
• Molecular Weight: 251.672
• Mol File: 1160285-30-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)-2-hydroxyacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)-2-hydroxyacetamide(1160285-30-2)
• EPA Substance Registry System: N-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)-2-hydroxyacetamide(1160285-30-2)

Safety Data

• Hazardous Substances Data: 1160285-30-2(Hazardous Substances Data)

Upstream product

• 79-14-1 glycolic Acid 
• 78583-81-0 3-(4-chlorophenyl)-1H-pyrazol-5-amine 

Relevant articles and documents

Botulinum neurotoxin serotype A inhibitors: Small-molecule mercaptoacetamide analogs

Botulinum neurotoxin elicits its paralytic activity through a zinc-dependant metalloprotease that cleaves proteins involved in neurotransmitter release. Currently, no drugs are available to reverse the effects of botulinum intoxication. Herein we report the design of a novel series of mercaptoacetamide small-molecule inhibitors active against botulinum neurotoxin serotype A. These analogs show low micromolar inhibitory activity against the isolated enzyme. Structure-activity relationship studies for a series of mercaptoacetamide analogs of 5-amino-3-phenylpyrazole reveal components essential for potent inhibitory activity.