1160309-52-3

Basic information

• Product Name: (Z)-4'-chloro-7-methoxy-3-styrylchromone
• Synonyms: (Z)-4'-chloro-7-methoxy-3-styrylchromone
• CAS NO: 1160309-52-3
• Molecular Weight: 312.752
• Mol File: 1160309-52-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-4'-chloro-7-methoxy-3-styrylchromone(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4'-chloro-7-methoxy-3-styrylchromone(1160309-52-3)
• EPA Substance Registry System: (Z)-4'-chloro-7-methoxy-3-styrylchromone(1160309-52-3)

Safety Data

• Hazardous Substances Data: 1160309-52-3(Hazardous Substances Data)

Upstream product

• 42059-56-3 7-methoxy-3-formylchromone 
• 1530-39-8 (4-chlorobenzyl)triphenylphosphonium chloride 

Downstream Products

• 1174670-24-6 (Z)-4-(4-chlorostyryl)-3⁽⁵⁾-(2-hydroxy-4-methoxyphenyl)pyrazole 

Relevant articles and documents

Syntheses of (E)- and (Z)-3-styrylchromones

Several (E)- and (Z)-3-styrylchromones were prepared by two different methodologies, the Wittig reaction of chromone-3-carboxaldehyde with benzylic ylides and the Knoevenagel condensation of chromone-3-carboxaldehyde with phenylacetic acids in the presence of potassium tert-butoxide under microwave irradiation. The Knoevenagel reaction followed by a decarboxylation offered an efficient and diastereoselective method for preparing (E)-3-styrylchromones in a shorter reaction time. It was also demonstrated that phenylacetic acid can also be substituted with success by phenylmalonic acid. The stereochemistry of all products was assigned by NMR experiments.