116049-66-2Relevant academic research and scientific papers
Stereoselective hydride reductions of chiral 2-p-tolylsulfinylcycloalkanones
Bueno, Ana B.,Carmen Carreno,Garcia Ruano, Jose L.,Pena, Begona,Rubio, Almudena,Hoyos, Miguel A.
, p. 9355 - 9364 (2007/10/02)
The highly stereoselective hydride reductions of chiral 2-p-tolylsulfinyl-cyclopentanones and- cycloheptanones are described. With DIBAL (electrophilic hydride) the configuration induced at C-1 is controlled by the sulfinyl group (1,3-asymmetric induction
SYNTHESIS AND REDUCTION OF CHIRAL SULFINYL CYCLOHEXANONES
Carreno, M.C.,Ruano, J.L.Garcia,Rubio, A.
, p. 4861 - 4864 (2007/10/02)
The reaction of cyclohexanone with (S)-(-)-menthyl-p-toluenesulfinate in the presence of i-Pr2NMgBr yields a mixture of enantiomerically pure 2-p-tolylsulfinylcyclohexanone diastereoisomers.Their stereoselective reduction to chiral hydroxysulfoxides is also reported.
