1160608-64-9

Upstream product

• 6575-24-2 2-(2,6-dichlorophenyl)acetic acid 
• 61875-53-4 2,6-dichlorophenylacetylchloride 
• 1160608-53-6 2-(2,6-dichlorophenyl)-N-(4,6-dichloropyrimidin-5-yl)acetamide 

Downstream Products

• 1160606-87-0 [2-(2,6-Dichloro-benzyl)-oxazolo[5,4-d]pyrimidin-7-yl-]-(4-trifluoromethyl-phenyl)-amine 

Relevant academic research and scientific papers

AMINOPYRIDINE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS

The invention relates to compound of the formula (I) in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.

Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of TRPV1

Certain TRPV1-modulating imidazolo-, oxazolo-, and thiazolopyrimdine compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPV1 activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease.