1160616-08-9Relevant academic research and scientific papers
Synthesis of enantiopure α-chlorocyclobutanones and cyclobutanols as scaffolds for the diverted synthesis of serine protease inhibitors
Yang, Gaoqiang,Ghosez, Leon
experimental part, p. 1738 - 1748 (2009/08/17)
Synthetic paths towards highly functionalized α-chlorocyclobutanone scaffolds susceptible to lead to serine proteases inhibitors were explored. The syntheses started from bicyclic α-chlorocyclobutanones 3, which are readily available from Seebach's oxazol
