1160642-01-2Relevant academic research and scientific papers
General multicomponent strategy for the synthesis of 2-Amino-l,4- diazaheterocycles: Scope, limitations, and utility
Kysil, Volodymyr,Khvat, Alexander,Tsirulnikov, Sergey,Tkachenko, Sergey,Williams, Caroline,Churakova, Marina,Ivachtchenko, Alexandre
experimental part, p. 1525 - 1543 (2010/06/16)
Multicomponent reactions of primary 1,2- and 1,3-diamines with carbonyl compounds and isocyanides resulting in the formation of diverse 2-amino-l,4-diazaheterocycles are described. Lewis acids (LAs) promote the reactions effectively, and chlorotrimethylsi
Multicomponent approach to unique 1,4-diazepine-2-amines
Kysil, Volodymyr,Khvat, Alexander,Tsirulnikov, Sergey,Tkachenko, Sergey,Ivachtchenko, Alexandre
experimental part, p. 2854 - 2856 (2009/09/06)
Isocyanide-based multicomponent reaction (IMCR) of 1,3-diaminopropane with carbonyl compounds has been developed as an efficient strategy for the synthesis of 1,4-diazepine-2-amines. Br?nsted and Lewis acids are able to promote the reaction, and TMSCl has
