1160744-75-1Relevant academic research and scientific papers
A direct C-C cross-coupling of alcohols at the β-position with aldehydes under co-promotion of tris(triphenylphosphine)-rhodium chloride/boron trifuoride etherate
Zhang, Shu-Yu,Tu, Yong-Qiang,Fan, Chun-An,Jiang, Yi-Jun,Shi, Lei,Cao, Ke
supporting information; experimental part, p. 2189 - 2193 (2009/10/02)
The novel tris(triphenylphosphine)rhodium chloride/boron trifuoride etherate [RhCl-(PPh3)3/BF3·OEt 2] co-promoted the C-C cross-coupling of tertiary alcohols at the β-position with aldehydes. This reaction provides an efficient synthesis of either structurally diverse 1,3-diols or polysubstituted tetrahydropyrans by controlling the substrate structures, and it could be developed to a practical syntheticmet hod for numerous natural products and medicinally important compounds.
