116076-80-3Relevant academic research and scientific papers
Visible light-mediated arylalkylation of allylic alcohols through concomitant 1,2-aryl migration
Huang, Hong-Li,Yan, Hang,Yang, Chao,Xia, Wujiong
, p. 4910 - 4913 (2015)
A photocatalytic process for selective arylalkylation of allylic alcohols with α-bromo diethyl malonate has been developed. The reaction provided a straightforward approach to synthesize α-aryl-β-alkylated ketones via unique 1,2-aryl migration. The procedure is highlighted by its operational simplicity and mild reaction conditions.
Polar Effects in Radical Addition Reactions: Borderline Cases
Giese, Bernd,He, Jianing,Mehl, Wolf
, p. 2063 - 2066 (2007/10/02)
Methyl radicals substituted by one ester or nitrile group are on the borderline between nucleophilic and electrophilic behavior.In addition reactions of these borderline radicals to styrenes, polar effects of both, electron-withdrawing and electron-donating substituents at the alkene, increase the rates.But these polar effects are smaller compared to those of nucleophilic or electrophilic radicals.In consequence, the stability of the radicals formed during the addition of the borderline radicals to styrenes are of major importance for the rate of the reaction.
