1160843-96-8Relevant articles and documents
Palladium-catalyzed direct C-4 arylation of 2,5-disubstituted furans with aryl bromides
Gottumukkala, Aditya L.,Doucet, Henri
supporting information; experimental part, p. 2183 - 2188 (2009/10/02)
A simple and atom-economic procedure for the selective C-4 arylation of 2,5-disubstituted furans via C-H bond activation using electron-deficient aryl bromides is reported. Only 0.5 mol% of the commercially available dimeric (allene)palladium chloride, [Pd(C3H5)Cl]2, was employed as catalyst. This environmentally attractive procedure has been found to be tolerant to a variety of functional groups on the aryl bromide such as carbonyl, nitrile, nitro, fluoro, ester or trifluoromethyl.