1160927-33-2Relevant academic research and scientific papers
Polyamide amino acids: A new class of RNA ligands
Bonnard, Vanessa,Azoulay, Stephane,Di Giorgio, Audrey,Patino, Nadia
supporting information; experimental part, p. 2302 - 2304 (2009/09/05)
This communication introduces a new class of promising RNA ligands, named polyamide amino acids (PAA), which are able to bind a targeted bulged stem-loop RNA fragment (HIV-1 TAR RNA) with micromolar affinities and with specificity comparative to dsDNA and tRNA; both the affinity and the specificity of PAA for TAR depend on their length and on the nature of the amino acid residues. The Royal Society of Chemistry 2009.
