1160937-42-7Relevant articles and documents
Synthesis of macrocyclic lactams from 2-(ω-amino-alkyl)-2-benzoylamino-3-phenyl-N,N-dimethylpropan-amides via direct amide cyclization
Fritschi, Stephan P.,Linden, Anthony,Heimgartner, Heinz
, p. 985 - 1005 (2009)
The alkylation of 4-benzyl-2-phenyl-1,3-oxazol-5(4H)-one (11) with (ω-azidoalkyl iodides (12) by deprotonation with LDA in THF/HMPT at -78 °C yielded mixtures of the 4,4-disubstituted l,3-oxazol-5(4H)-ones (13) and the O-alkylated 1,3-oxazoles (14) in 65-