116114-19-3Relevant academic research and scientific papers
GPR139 RECEPTOR MODULATORS
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Page/Page column 76, (2021/06/26)
Compounds are provided that modulate the GPR139 receptor, compositions containing the same, and to methods of their preparation and use for treatment of a malcondition wherein modulation of the GPR139 receptor is medically indicated or beneficial. Such compounds have the structure of Formula (I): or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein R1, R4, R5, R9, R10, Q6, Q7, and Q12 are as defined herein.
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents
Kane,Baron,Dudley,Sorensen,Staeger,Miller
, p. 2772 - 2777 (2007/10/02)
A series of 5-aryl-2,4-dihydro-3H-1,2,4-triazol-3-ones was evaluated for anticonvulsant activity. In general the members of this series were prepared by the alkaline crystalization of 1-aroyl-4-alkylsemicarbazides. The resulting 2-unsubstituted 3H-1,2,4-t
The Bis(tricyclohexylstannyl) Sulfide Thionation of 3H-1,2,4-Triazol-3-ones
Kane, John M.
, p. 912 - 914 (2007/10/02)
5-Aryl-2,4-dialkyl-2,4-dihydro-3H-1,2,4-triazol-3-ones may be converted in 55-74percent yield to the corresponding 3H-1,2,4-triazole-3-thiones by using the combination bis(tricyclohexylstannyl) sulfide/boron trichloride.
