116120-17-3

Upstream product

• 4393-09-3 2,3-dimethoxybenzyl amine 
• 5470-95-1 oxime of 2,3-dimethoxy-benzaldehyde 
• 116120-11-7 N-(2,3-Dimethoxy-benzyl)-2-(6-hydroxymethyl-benzo[1,3]dioxol-5-yl)-acetamide 

Downstream Products

• 116120-18-4 N-(2,3-Dimethoxy-benzyl)-2,2,2-trifluoro-N-[2-(6-formyl-benzo[1,3]dioxol-5-yl)-ethyl]-acetamide 
• 116182-61-7 (13R,13aS)-9,10-Dimethoxy-13-p-tolylsulfanyl-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline 
• 116120-16-2 (13S,13aS)-9,10-Dimethoxy-13-p-tolylsulfanyl-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline 
• 116120-14-0 (R)-6-(2,3-Dimethoxy-benzyl)-5-((R)-toluene-4-sulfinylmethyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline 
• 116120-14-0 (S)-6-(2,3-Dimethoxy-benzyl)-5-((R)-toluene-4-sulfinylmethyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline 
• 116120-12-8 N-(2,3-Dimethoxy-benzyl)-2,2,2-trifluoro-N-(2-{6-[(Z)-2-((R)-toluene-4-sulfinyl)-vinyl]-benzo[1,3]dioxol-5-yl}-ethyl)-acetamide 
• 116120-12-8 N-(2,3-Dimethoxy-benzyl)-2,2,2-trifluoro-N-(2-{6-[(E)-2-((R)-toluene-4-sulfinyl)-vinyl]-benzo[1,3]dioxol-5-yl}-ethyl)-acetamide 

Relevant academic research and scientific papers

INTRAMOLECULAR ADDITION OF AMINES TO CHIRAL VINYL SULFOXIDES, TOTAL SYNTHESIS OF (R)-(+)-CANADINE

The intramolecular conjugate addition of an amine to the chiral vinyl sulfoxides 3 and 4 to give chiral isoquinolines 5 and 6 is reported.Isoquinoline 5 is converted to (R)-(+)-Canadine via an intramolecular Pummerer reaction.