Tetrahedron Letters p. 4737 - 4740 (1987)
Update date:2022-07-29
Topics:
Pyne, Stephen G.
The intramolecular conjugate addition of an amine to the chiral vinyl sulfoxides 3 and 4 to give chiral isoquinolines 5 and 6 is reported.Isoquinoline 5 is converted to (R)-(+)-Canadine via an intramolecular Pummerer reaction.
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Doi:10.1021/acs.joc.6b01593
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(1987)Doi:10.1021/jo900606j
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(2012)
