116142-86-0Relevant academic research and scientific papers
Catalytic asymmetric [4+2]-cycloaddition of dienes with aldehydes
Liu, Luping,Kim, Hyejin,Xie, Youwei,Fares, Christophe,Kaib, Philip S.J.,Goddard, Richard,List, Benjamin
, p. 13656 - 13659 (2017)
Despite its significant potential, a general catalytic asymmetric [4+2]-cycloaddition of simple and electronically unbiased dienes with any type of aldehyde has long been unknown. Previously developed methodologies invariably require activated, electronically engineered substrates. We now provide a general solution to this problem. We show that highly acidic and confined imidodiphosphorimidates (IDPis) are extremely effective Br?nsted acid catalysts of the hetero-Diels-Alder reaction of a wide variety of aldehydes and dienes to give enantiomerically enriched dihydropyrans. Excellent stereoselectivity is generally observed and a variety of scents and natural products can be easily accessed.
Stereoselective C-Glycosidation of Glycals with Organoaluminum Reagents
Maruoka, Keiji,Nonoshita, Katsumasa,Itoh, Takayuki,Yamamoto, Hisashi
, p. 2215 - 2216 (2007/10/02)
A new approach to the stereoselective synthesis of C-glycosides from glycals with various organoaluminum reagents has been demonstrated.
