116159-23-0

Upstream product

• 116159-22-9 (E)-5-[(2R,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-oxiranyl]-3-methyl-pent-2-en-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 37905-03-6 8-hydroxygeranyl acetate 

Downstream Products

• 116159-24-1 3-((2R,3R)-3-{2-[(2R,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-oxiranyl]-ethyl}-3-methyl-oxiranyl)-propionaldehyde 
• 154912-81-9 tert-Butyl-((2R,3R)-3-{2-[(2R,3R)-3-(4-methoxy-benzyloxymethyl)-2-methyl-oxiranyl]-ethyl}-2-methyl-oxiranylmethoxy)-diphenyl-silane 
• 154911-21-4 (2S,3R)-3-{2-[(2R,3R)-3-(4-Methoxy-benzyloxymethyl)-2-methyl-oxiranyl]-ethyl}-2-methyl-oxirane-2-carbaldehyde 
• 154911-22-5 (E)-1-((2R,3R)-3-{2-[(2R,3R)-3-(4-Methoxy-benzyloxymethyl)-2-methyl-oxiranyl]-ethyl}-2-methyl-oxiranyl)-pent-1-en-3-one 
• 154911-24-7 C₅₄H₇₀O₁₂ 
• 154912-85-3 C₅₄H₇₀O₁₂ 
• 154912-87-5 C₅₉H₈₄O₁₂Si 

Relevant academic research and scientific papers

Studies in biomimetic polyether synthesis: Construction of an ABCD-ring subunit of etheromycin using polyepoxide cascade cyclisations

The diepoxides 8 and 9 were prepared by Horner-Emmons and aldol coupling reations from 21 and 13, respectively. The derived β-diketones 22 and 24 were cyclised under acidic conditions to generate the C1-C22 segment 7, which contains

STUDIES IN POLYETHER SYNTHESIS USING POLYEPOXYDE CYCLISATIONS.

The acid-catalysed directed cyclisation of mono-, di-, and triepoxy t-butyl ester derivatives is used for the asymmetric synthesis of various polyether-type fragments including a C13-C27 fragment of etheromycin.The epoxide stereochemistry is set up by Sharpless epoxidation of allylic and homoallylic alcohols.