116180-70-2

Upstream product

• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 104310-57-8 1-bromo-1-(3,4-dimethoxyphenyl)-1(E)-propene 

Downstream Products

• 116180-71-3 (3R,4S)-2,2-Dichloro-4-(3,4-dimethoxyphenyl)-3-methyl-4-p-tolylthiobutyrolactone 
• 116180-73-5 (3S,4R)-4-(3,4-Dimethoxyphenyl)-3-methyl-γ-butyrolactone 
• 116097-28-0 (4S,5R)-5-(3,4-Dimethoxy-phenyl)-5-ethoxy-4-methyl-dihydro-furan-2-one 
• 116097-29-1 (3S,4R)-4-(3,4-Dimethoxyphenyl)-2-methoxycarbonyl-3-methyl-γ-butyrolactone 
• 116180-72-4 (3S,4S)-4-(3,4-Dimethoxyphenyl)-3-methyl-4-p-tolylthio-γ-butyrolactone 
• 116097-30-4 (3S,4R)-4-(3,4-Dimethoxyphenyl)-2-methoxycarbonyl-3-methyl-2-(3-oxobutyl)-γ-butyrolactone 

Relevant academic research and scientific papers

Sulfoxide-Directed Lactonization: Asymmetric Synthesis of Porosin Intermediates

The application of a chiral sulfoxide-directed lactonization to the synthesis of a precursor of the neolignan porosin, in optically active form, is described.The methodology provides an efficient access to 3,4-disubstituted γ-butyrolactones with complete