116180-72-4

Upstream product

• 116180-70-2 (S)-(E)-1-(3,4-Dimethoxyphenyl)prop-1-enyl p-toluene sulfoxide 
• 104310-57-8 1-bromo-1-(3,4-dimethoxyphenyl)-1(E)-propene 
• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 116180-71-3 (3R,4S)-2,2-Dichloro-4-(3,4-dimethoxyphenyl)-3-methyl-4-p-tolylthiobutyrolactone 
• 104329-38-6 1,2-Dimethoxy-4-[(E)-1-(toluene-4-sulfinyl)-propenyl]-benzene 
• 10439-23-3 4-methylbenzenesulfinyl chloride 
• 104310-49-8 (4S,5R)-3,3-Dichloro-5-(3,4-dimethoxy-phenyl)-4-methyl-5-p-tolylsulfanyl-dihydro-furan-2-one 

Downstream Products

• 116180-73-5 (3S,4R)-4-(3,4-Dimethoxyphenyl)-3-methyl-γ-butyrolactone 
• 116097-28-0 (4S,5R)-5-(3,4-Dimethoxy-phenyl)-5-ethoxy-4-methyl-dihydro-furan-2-one 
• 116097-30-4 (3S,4R)-4-(3,4-Dimethoxyphenyl)-2-methoxycarbonyl-3-methyl-2-(3-oxobutyl)-γ-butyrolactone 
• 116097-29-1 (3S,4R)-4-(3,4-Dimethoxyphenyl)-2-methoxycarbonyl-3-methyl-γ-butyrolactone 
• 104310-54-5 (4R,5R)-5-(3,4-Dimethoxy-phenyl)-4-methyl-dihydro-furan-2-one 
• 104310-54-5 (4S,5R)-5-(3,4-Dimethoxy-phenyl)-4-methyl-dihydro-furan-2-one 

Relevant academic research and scientific papers

Sulfoxide-Directed Lactonization: Asymmetric Synthesis of Porosin Intermediates

The application of a chiral sulfoxide-directed lactonization to the synthesis of a precursor of the neolignan porosin, in optically active form, is described.The methodology provides an efficient access to 3,4-disubstituted γ-butyrolactones with complete

Stereospecific synthesis of γ-butyrolactones from acyclic vinyl sulfoxides: an asymmetric synthesis of optically pure oak lactones

The sulfoxide-directed lactonization of several trisubstituted vinyl sulfoxides with dichloroketene proceeds in a completely stereospecific manner. The lactonization of (E) -3 (R) -p-tolylsulfinyloctene occurs with complete enantiospecificity to produce a precursor for the synthesis of optically pure oak lactones.