1161923-89-2Relevant academic research and scientific papers
An efficient one-pot synthesis of 5-(substituted amino)-1,2,4-thia- and -oxa-diazoles
Dueruest, Yasar,Yildirim, Muhammet,Aycan, Asli
experimental part, p. 235 - 239 (2009/08/07)
A general protocol for the synthesis of 5-(substituted amino)-1,2,4- thiadiazoles by the cyclocondensation reaction of amidoximes with N-substituted thioureas in the presence of KF/Al2O3, and of 5-(cyclohexylamino)-1,2,4-oxadiazoles with DCC in the presence of KF/Al 2O3 and thiourea, is described. The structures of the new compounds were elucidated by spectroscopic and physical data, and the crystal structure determination by X-ray diffraction of three examples.
