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benzyl-(2S)-2-[(R)-1-acetoxy-2-oxo-1-(phenethyl)prop-3-ylcarbamoyl]-4-oxopyrrolidinedine-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1162084-58-3

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1162084-58-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1162084-58-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,2,0,8 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1162084-58:
(9*1)+(8*1)+(7*6)+(6*2)+(5*0)+(4*8)+(3*4)+(2*5)+(1*8)=133
133 % 10 = 3
So 1162084-58-3 is a valid CAS Registry Number.

1162084-58-3Relevant academic research and scientific papers

Convenient synthesis and evaluation of biological activity of benzyl (2S)-2-[(R)-1-hydroxy-2-oxo-(1-phenethyl)prop-3-ylcarbamoyl]-4-oxopiperidine- (or -4-oxopyrrolidine)-1-carboxylate as novel histone deacetylase inhibitors

Oh, Seikwan,Moon, Hyung-In,Jung, Jae-Chul

, p. 1300 - 1304 (2008)

A simple synthesis, involving a key coupling reaction, and the biological activity of the title compounds 16 and 17 are described. The key fragments are the amine·HCl salt 6 and the acids 9 and 13, which were smoothly coupled by using ethyl(dimethylaminopropyl)carbodiimide (EDCI) and 1- hydroxybenzotriazole (HOBt) in high yield. We have found that the in vitro growth inhibitory potency of the new compounds 16 and 17 exhibits good histone deacetylase (HDAC) activity.

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